Article 1

Tubulopathy cohort conditions The Hypokalaemic Alkaloses cohort has been renamed Tubulopathy. It now includes the following conditions:

• Autoimmune distal renal tubular acidosis

• Autosomal dominant distal renal tubular acidosis

• Autosomal recessive distal renal tubular acidosis • Autosomal recessive proximal renal tubular acidosis

• Bartter Syndromes Type 1

• Bartter Syndrome Type 2

• Bartter Syndrome Type 3

• Bartter Syndrome type 4

• Dominant hypophosphatemia with nephrolithiasis or osteoporosis

• Drug induced Fanconi syndrome

• Drug induced hypomagnesemia

• Drug induced Nephrogenic Diabetes Insipidus

• EAST syndrome (Epilepsy, Ataxia, Sensorineural deafness, Tubulopathy)

• Familial Hypomagnesaemia with hypercalciuria and nephrocalcinosis CLDN16/19

• Familial primary hypomagnesemia with hypocalcuria FXYD2

• Familial primary hypomagnesemia with normocalcuria EGF

• Familial renal glucosuria SLC5A2

• Fanconi Renotubular syndrome 1 (FRTS1)

• Fanconi Renotubular syndrome 2 (FRTS2)

• Fanconi Renotubular syndrome 3 (FRTS3)

• Generalized pseudohypoaldosteronism type 1

• Gitelman syndrome

• Heavy metal induced Fanconi syndrome

• Hereditary renal hypouricemia

• Hereditary hypophosphatemic rickets with hypercalciuria

• Isolated autosomal dominant hypomagnesemia, Glaudemans type

• Liddle syndrome

• Nephrogenic diabetes insipidus

• Nephrogenic syndrome of inappropriate antidiuresis

• Oncogenic osteomalacia

• Osteopetrosis with renal tubular acidosis

• Primary hypomagnesemia with secondary hypocalcemia

• Pseudohypoaldosteronism type 2A

• Pseudohypoaldosteronism type 2B

• Pseudohypoaldosteronism type 2C • Pseudohypoaldosteronism type 2E • Renal pseudohypoaldosteronism type 1